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Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

17 Feb 2023

Abstract excerpt

BACKGROUND: High-throughput screening (HTS) of small molecule drug libraries has greatly facilitated the discovery of new cancer drugs. However, most phenotypic screening platforms used in the field of oncology are based solely on cancer cell populations and do not allow for the identification of immunomodulatory agents. METHODS: We developed a phenotypic screening platform based on a miniaturized co-culture...

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PMID: 36803614
DOI: 10.1186/s12885-023-10645-4

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