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Article

Chemotherapy Enriches for Proinflammatory Macrophage Phenotypes that Support Cancer Stem-Like Cells and Disease Progression in Ovarian Cancer.

Cancer research communications - 1 Oct 2024

Cruz Luisjesus S, Robinson Mikella, Stevenson Denay, Amador Isabella C, Jordan Gregory J, Valencia Sofia, Navarrete Carolina, House Carrie D

Abstract excerpt

High-grade serous ovarian cancer remains a poorly understood disease with a high mortality rate. Although most patients respond to cytotoxic therapies, a majority will experience recurrence. This may be due to a minority of drug-resistant cancer stem-like cells (CSC) that survive chemotherapy and are capable of repopulating heterogeneous tumors. It remains unclear how CSCs are supported in the tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39287565
DOI: 10.1158/2767-9764.CRC-24-0311
PMCID: PMC11464072

Genes

CCL2
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Chemotherapy Enriches for Proinflammatory Macrophage Phenotypes that Support Cancer Stem-Like Cells and Disease Progression in Ovarian Cancer.PMID 39287565Read ↗

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