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Article

Phenotypic screening in cancer drug discovery - past, present and future.

Nature reviews. Drug discovery - 1 Aug 2014

Moffat John G, Rudolph Joachim, Bailey David

Abstract excerpt

There has been a resurgence of interest in the use of phenotypic screens in drug discovery as an alternative to target-focused approaches. Given that oncology is currently the most active therapeutic area, and also one in which target-focused approaches have been particularly prominent in the past two decades, we investigated the contribution of phenotypic assays to oncology drug discovery by analysing the...

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PMID: 25033736
DOI: 10.1038/nrd4366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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