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Article

Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

1 Nov 2021

Abstract excerpt

Statins are among the most commonly prescribed drugs, and around every fourth person above the age of 40 is on statin medication. Therefore, it is of utmost clinical importance to understand the effect of statins on cancer cell plasticity and its consequences to not only patients with cancer but also patients who are on statins. Here, we find that statins induce a partial epithelial-to-mesenchymal transition...

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PMID: 34818551
DOI: 10.1016/j.celrep.2021.110056

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