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Article

Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 2 Oct 2012

Schulz Martin Michael Peter, Reisen Felix, Zgraggen Silvana, Fischer Stephanie, Yuen Don, Kang Gyeong Jin, Chen Lu, Schneider Gisbert, Detmar Michael

Abstract excerpt

Lymphangiogenesis plays an important role in promoting cancer metastasis to sentinel lymph nodes and beyond and also promotes organ transplant rejection. We used human lymphatic endothelial cells to establish a reliable three-dimensional lymphangiogenic sprouting assay with automated image acquis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22949700
DOI: 10.1073/pnas.1206036109
PMCID: PMC3479568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22949700-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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