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Epigenome-wide analysis of aging effects on liver regeneration

13 Feb 2023

Abstract excerpt

BACKGROUND: Aging is known to exert an effect on liver regeneration, with the ability of liver to regenerate displaying a significant decline over time. Liver physiological parameters such as liver volume, blood flow, and metabolism, as well as the ability to regenerate after injury have all been shown to decrease at old age in humans and model systems, with a number of molecular mechanisms proposed to be...

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PMID: 36782243
DOI: 10.1186/s12915-023-01533-1

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