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Genetic analysis of heterogeneous subsets of circulating tumour cells from high grade serous ovarian carcinoma patients

13 Feb 2023

Abstract excerpt

Abstract Circulating tumour cells (CTCs) are heterogenous and contain genetic information from the tumour of origin. They bear specific intra- and extra-cellular protein markers aiding in their detection. However, since these markers may be shared with other rare cells in the blood, only genetic testing can confirm their malignancy. Herein, we analyse different CTC subsets using single cell whole genome DNA...

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PMID: 36781954
DOI: 10.1038/s41598-023-29416-z

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