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Article

IL-11 drives the phenotypic transformation of tracheal epithelial cells and fibroblasts to enhance abnormal repair after tracheal injury.

Biochimica et biophysica acta. Molecular cell research - 1 Apr 2023

Xiao Rui, Gu Lei, Li An-Mao, Gan Yi-Ling, He Chun-Yan, Liao Jia-Xin, Li Yi-Shi, Xu Li, Guo Shu-Liang

Abstract excerpt

Tracheal stenosis (TS) is a multifactorial and heterogeneous disease that can easily lead to respiratory failure and even death. Interleukin-11 (IL-11) has recently received increased attention as a fibrogenic factor, but its function in TS is uncertain. This study aimed to investigate the role of IL-11 in TS regulation based on clinical samples from patients with TS and a rat model of TS produced by nylon brush...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36758859
DOI: 10.1016/j.bbamcr.2023.119438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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