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Article

Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease

21 Jan 2016

Abstract excerpt

In this article, we review the biology and physiological importance of transforming growth factor-β (TGF-β) to homeostasis in the respiratory system, its importance to innate and adaptive immune responses in the lung, and its pathophysiological role in various chronic pulmonary diseases including pulmonary arterial hypertension, chronic obstructive pulmonary disease, asthma, and pulmonary fibrosis. The TGF-β...

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PMID: 26796672
DOI: 10.1165/rcmb.2015-0391tr

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