Article
Molecular Mechanisms and Physiological Changes behind Benign Tracheal and Subglottic Stenosis in Adults.
International journal of molecular sciences - 22 Feb 2022
Marchioni Alessandro, Tonelli Roberto, Andreani Alessandro, Cappiello Gaia Francesca, Fermi Matteo, Trentacosti Fabiana, Castaniere Ivana, Fantini Riccardo, Tabbì Luca, Andrisani Dario, Gozzi Filippo, Bruzzi Giulia, Manicardi Linda, Moretti Antonio, Baroncini Serena, Samarelli Anna Valeria, Pinelli Massimo, De Santis Giorgio, Stefani Alessandro, Marchioni Daniele, Mattioli Francesco, Clini Enrico
Abstract excerpt
Laryngotracheal stenosis (LTS) is a complex and heterogeneous disease whose pathogenesis remains unclear. LTS is considered to be the result of aberrant wound-healing process that leads to fibrotic scarring, originating from different aetiology. Although iatrogenic aetiology is the main cause of subglottic or tracheal stenosis, also autoimmune and infectious diseases may be involved in causing LTS. Furthermore,...
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