Article

Transcriptional profiling sheds light on the fibrotic aspects of idiopathic subglottic tracheal stenosis

2024-02-21

Abstract excerpt

1 Idiopathic subglottic stenosis (ISGS) is a rare fibrotic disease of the upper trachea with an unknown pathomechanism. It typically affects adult Caucasian female patients, leading to severe airway constrictions caused by progressive scar formation and inflammation with clinical symptoms of dyspnoea, stridor and potential changes to the voice. Endoscopic treatment frequently leads to recurrence, whereas surgical...

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Literature Corpus work: ff3c6ef3-77fb-5818-92ca-27d1bc164518
DOI: 10.1101/2024.02.19.580975

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