[Sex-specific depression risk].

Abstract excerpt

Major depression displays significant heritability, and its genetic background has been extensively explored by genome-wide association studies. On the whole, these results indicate a highly polygenic landscape with significant sex-linked differences revealing a higher and more polygenic genetic influence in females than in males.

Topics

• Female
• Humans
• Male
• Depression
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Major Depressive Disorder
• Multifactorial Inheritance