Article
Virus induced dysbiosis promotes type 1 diabetes onset.
Frontiers in immunology - 1 Jan 2023
Morse Zachary J, Simister Rachel L, Crowe Sean A, Horwitz Marc S, Osborne Lisa C
Abstract excerpt
Autoimmune disorders are complex diseases of unclear etiology, although evidence suggests that the convergence of genetic susceptibility and environmental factors are critical. In type 1 diabetes (T1D), enterovirus infection and disruption of the intestinal microbiota are two environmental factors that have been independently associated with T1D onset in both humans and animal models. However, the possible...
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