Single-cell RNA-seq reveals cellular heterogeneity from deep fascia in patients with acute compartment syndrome

Abstract excerpt

Introduction: High stress in the compartment surrounded by the deep fascia can cause acute compartment syndrome (ACS) that may result in necrosis of the limbs. The study aims to investigate the cellular heterogeneity of the deep fascia in ACS patients by single-cell RNA sequencing (scRNA-seq). Methods: We collected deep fascia samples from patients with ACS (high-stress group, HG, n=3) and patients receiving...

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