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Characterization of Cell-Free DNA Size Distribution in Osteosarcoma Patients

3 Feb 2023

Abstract excerpt

PURPOSE: Cell-free DNA (cfDNA) analysis is a powerful tool for noninvasively predicting patient outcomes. We analyzed the size distribution of cfDNA and assessed its prognostic and diagnostic values in an osteosarcoma cohort. EXPERIMENTAL DESIGN: The fragment size distribution and level of cfDNA were analyzed in 15 healthy donors and 50 patients with osteosarcoma using automated capillary electrophoresis. The...

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PMID: 36735493
DOI: 10.1158/1078-0432.ccr-22-2912

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