Article
Size distribution of cell-free DNA in oncology.
Critical reviews in oncology/hematology - 1 Oct 2021
Udomruk Sasimol, Orrapin Santhasiri, Pruksakorn Dumnoensun, Chaiyawat Parunya
Abstract excerpt
Tumor-specific, circulating cell-free DNA (cfDNA) in liquid biopsy test is a novel promising biomarker in the advancement of cancer management, including early diagnosis, screening, prognosis, identification of actionable targets, and serial tumor monitoring. The specific size pattern of DNA fragments derived from cancer cells is observed to differ from that of cfDNA fragments shed by non-cancer cells. Research...
Topics
- Biomarkers, Tumor
- Cell-Free Nucleic Acids
- Humans
- Liquid Biopsy
- Medical Oncology
- Mutation
