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Article

Rpl3l gene deletion in mice reduces heart weight over time

17 Jan 2023

Abstract excerpt

Introduction: The ribosomal protein L3-like (RPL3L) is a heart and skeletal muscle-specific ribosomal protein and paralogue of the more ubiquitously expressed RPL3 protein. Mutations in the human RPL3L gene are linked to childhood cardiomyopathy and age-related atrial fibrillation, yet the function of RPL3L in the mammalian heart remains unknown. Methods and Results: Here, we observed that mouse cardiac...

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Identifiers

PMID: 36733907
DOI: 10.3389/fphys.2023.1054169

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