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Article

Anchored p90 ribosomal S6 kinase 3 is required for cardiac myocyte hypertrophy.

Circulation research - 4 Jan 2013

Li Jinliang, Kritzer Michael D, Michel Jennifer J Carlisle, Le Andrew, Thakur Hrishikesh, Gayanilo Marjorie, Passariello Catherine L, Negro Alejandra, Danial Joshua B, Oskouei Behzad, Sanders Michael, Hare Joshua M, Hanauer Andre, Dodge-Kafka Kimberly, Kapiloff Michael S

Abstract excerpt

RATIONALE: Cardiac myocyte hypertrophy is the main compensatory response to chronic stress on the heart. p90 ribosomal S6 kinase (RSK) family members are effectors for extracellular signal-regulated kinases that induce myocyte growth. Although increased RSK activity has been observed in stressed myocytes, the functions of individual RSK family members have remained poorly defined, despite being potential...

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Share to A Kinase Anchor Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoproterenol

Share to Myocytes, Cardiac

Share to Protein Interaction Domains and Motifs

Share to Protein Interaction Mapping

Share to Ribosomal Protein S6 Kinases, 90-kDa

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Source

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Identifiers

PMID: 22997248
DOI: 10.1161/CIRCRESAHA.112.276162
PMCID: PMC3537852

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