Article
Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer.
BMC cancer - 1 Feb 2023
Jung Max, Rose Michael, Knuechel Ruth, Loeffler Chiara, Muti Hannah, Kather Jakob Nikolas, Gaisa Nadine T
Abstract excerpt
AIMS: Immune checkpoint inhibitor (ICI) therapy has become a viable treatment strategy in bladder cancer. However, treatment responses vary, and improved biomarkers are needed. Crucially, the characteristics of immune cells remain understudied especially in squamous differentiated bladder cancer (sq-BLCA). Here, we quantitatively analysed the tumour-immune phenotypes of sq-BLCA and correlated them with PD-L1...
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