Article
Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes.
Scientific reports - 29 Jan 2020
Li Huili, Zhang Qingzhao, Shuman Lauren, Kaag Matthew, Raman Jay D, Merrill Suzanne, DeGraff David J, Warrick Joshua I, Chen Guoli
Abstract excerpt
Although advanced bladder cancer overall has a poor prognosis, a subset of patients demonstrate durable response to immune checkpoint inhibitors. Evidence shows that the response to checkpoint inhibitors may be associated with type and degree of immune infiltration in the tumor microenvironment. Here, we evaluated immune markers stratified by molecular subtypes and histologic variants. The study utilized a series...
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