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Article

The potential implication of MDR1 and NAC1 genetic polymorphisms on resistance to antiepileptic drugs among a Jordanian epileptic population: a cross-sectional study.

Annals of human biology - 1 Feb 2023

Abduljabbar Rami, Tamimi Duaa Eid, Yousef Al-Motassem

Abstract excerpt

BACKGROUND: Resistance to antiepileptic drugs (AEDs) remains one of the main challenges to neurologists. Polymorphisms of drug efflux transporters such as multidrug resistance (MDR1) gene and target sites such as the nucleus accumbens-associated 1 (NAC1) gene have been suggested to influence the responsiveness to treatment. AIM: Evaluation of the association of MDR1 and NAC1 polymorphisms with AEDs resistance...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36714955
DOI: 10.1080/03014460.2023.2173291

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