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Article

Exploring genes for immunoglobulin A nephropathy: a summary data-based mendelian randomization and FUMA analysis.

BMC medical genomics - 29 Jan 2023

Zhang Qian, Zhang Kang, Zhu Yining, Yuan Guangwei, Yang Jingyun, Zhang Minmin

Abstract excerpt

BACKGROUND: Immunoglobulin A nephropathy (IgAN) is a complex autoimmune disease, and the exact pathogenesis remains to be elucidated. This study aimed to explore genes underlying the pathogenesis of IgAN. METHODS: We conducted the summary data-based Mendelian randomization (SMR) analysis and performed functional mapping and annotation using FUMA to explore genetic loci that are potentially involved in the...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulonephritis, IGA

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36709307
DOI: 10.1186/s12920-023-01436-8
PMCID: PMC9884184

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