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Article

The Genetics of IgA Nephropathy: Implications for Future Therapies.

Seminars in nephrology - 1 Sept 2024

Zhou Xu-Jie, Zhang Hong

Abstract excerpt

IgA nephropathy (IgAN), the most prevalent primary glomerulonephritis worldwide, carries a considerable lifetime risk of kidney failure. The etiology of IgAN, however, remains incompletely understood, and effective treatment is lacking. Although the multihit model effectively identifies key steps in IgAN development and, to date, provides the best description of IgAN pathogenesis, it remains under development to...

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Identifiers

PMID: 40087125
DOI: 10.1016/j.semnephrol.2025.151567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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