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Article

Shared genetics of IgA nephropathy and cardiometabolic diseases revealed by integrative genomic analysis.

Renal failure - 1 Dec 2026

Dai Lu, Chen Guanglei, Yang Yinan, Yan Yiping, Zhao Qin, He Na, Xiang Yongjing, Li Zhengsheng, Chen Yunzhi

Abstract excerpt

Immunoglobulin A nephropathy (IgAN), the most common primary glomerular disease and a leading cause of end-stage kidney disease (ESKD), is associated with cardiovascular and metabolic abnormalities. To explore these genetic overlaps, we integrated large-scale GWAS data from IgAN, 21 pan-vascular diseases (PVDs), 13 metabolic traits, 11 immune cell phenotypes, and established IgAN risk factors. Cross-trait...

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Share to Cardiovascular Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glomerulonephritis, IGA

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Source

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Identifiers

PMID: 42535737
DOI: 10.1080/0886022X.2026.2706884
PMCID: PMC13431020

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