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Article

Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA

18 Oct 2018

Abstract excerpt

Abstract Biallelic mutations of the CCAAT/enhancer binding protein α (CEBPA) gene define a distinct genetic entity of acute myeloid leukemia (AML) with favorable prognosis. The presence of GATA2 and CSF3R mutations that are specifically associated with this subgroup but not mutated in all samples suggests a genetic heterogeneity of biCEBPA-mutated AML. We characterized the mutational landscape of CEBPA-mutated...

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Identifiers

PMID: 30337300
DOI: 10.1182/bloodadvances.2018016840

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