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Article

ADAD2 functions in spermiogenesis and piRNA biogenesis in mice

26 Jan 2023

Abstract excerpt

BACKGROUND: Adenosine deaminase domain containing 2 (ADAD2) is a testis-specific protein composed of a double-stranded RNA binding domain and a non-catalytic adenosine deaminase domain. A recent study showed that ADAD2 is indispensable for the male reproduction in mice. However, the detailed functions of ADAD2 remain elusive. OBJECTIVES: This study aimed to investigate the cause of male sterility in Adad2 mutant...

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PMID: 36698249
DOI: 10.1111/andr.13400

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