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Article

Matrix Metalloproteinases and Their Inhibitors in Chronic Obstructive Pulmonary Disease.

Archivum immunologiae et therapiae experimentalis - 1 Jun 2016

Navratilova Zdenka, Kolek Vitezslav, Petrek Martin

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is characterised by irreversible airflow limitation associated with chronic inflammation. Matrix metalloproteinases (MMPs) are proteolytic enzymes that contribute to the inflammatory response in COPD and degrade extracellular matrix components. Their enzymatic activity is inhibited by a four-member family of tissue inhibitors of metalloproteinases (TIMPs). In COPD, the...

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PMID: 26611761
DOI: 10.1007/s00005-015-0375-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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