Article

LACC1 attenuates LPS-induced acute lung injury by inhibiting inflammatory response in alveolar macrophage through LPAR3/PI3K/AKT/mTOR signaling pathway

2026-03-08

Abstract excerpt

<title>Abstract</title> <p> Objective Laccase domain containing 1 (LACC1) is an enzyme abundantly expressed in inflammatory macrophages that regulate diverse inflammatory diseases. This study aimed to investigate the role of LACC1 in lipopolysaccharide (LPS)-induced acute lung injury (ALI) and to elucidate its underlying regulatory mechanisms. Methods Single-cell RNA sequencing of bronchoalveolar lavage fluid...

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Literature Corpus work: 4c5430ed-1503-5e21-a658-1cd8d5cf5e6f
DOI: 10.21203/rs.3.rs-8929971/v1

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