Article
Notch Partners in the Long Journey of T-ALL Pathogenesis.
International journal of molecular sciences - 10 Jan 2023
Toribio María Luisa, González-García Sara
Abstract excerpt
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological disease that arises from the oncogenic transformation of developing T cells during T-lymphopoiesis. Although T-ALL prognosis has improved markedly in recent years, relapsing and refractory patients with dismal outcomes still represent a major clinical issue. Consequently, understanding the pathological mechanisms that lead to the...
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