Article
Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.
The Journal of pathology - 1 Jan 2011
Aster Jon C, Blacklow Stephen C, Pear Warren S
Abstract excerpt
Notch receptors participate in a highly conserved signalling pathway that regulates normal development and tissue homeostasis in a context- and dose-dependent manner. Deregulated Notch signalling has been implicated in many diseases, but the clearest example of a pathogenic role is found in T-cel...
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