Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-124-3p mediates polygenic risk shared between schizophrenia and bipolar disorder.

Neuron - 18 Jan 2023

Żurawek Dariusz, Turecki Gustavo

Abstract excerpt

In this issue of Neuron, Namkung et al. demonstrate that the microRNA miR-124-3p is associated with polygenic risk scores shared between schizophrenia and bipolar disorder and confers risk to behavioral alterations common to these two disorders through modulation of AMPA receptor neurotransmission.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Genetic Predisposition to Disease
Share to MicroRNAs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multifactorial Inheritance

Share to Risk Factors

Share to Schizophrenia

Source

Identifiers

PMID: 36657396
DOI: 10.1016/j.neuron.2022.12.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-124-3p mediates polygenic risk shared between schizophrenia and bipolar disorder.PMID 36657396Read ↗

The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorderSemantic proximity Read ↗

Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation.Semantic proximity Read ↗

Genetic risk for schizophrenia: convergence on synaptic pathways involved in plasticity.Semantic proximity Read ↗

Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder.Semantic proximity Read ↗

Bioinformatic analyses and conceptual synthesis of evidence linking ZNF804A to risk for schizophrenia and bipolar disorder.Semantic proximity Read ↗

The schizophrenia susceptibility gene ZNF804A confers risk of major mood disorders.Semantic proximity Read ↗

Phosphoinositide-3-kinase regulatory subunit 1 gene polymorphisms are associated with schizophrenia and bipolar disorder in the Han Chinese population.Semantic proximity Read ↗

Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants.Semantic proximity Read ↗

Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairmentSemantic proximity Read ↗

Association between the zinc finger protein 804A (ZNF804A) gene and the risk of schizophrenia and bipolar I disorder across diagnostic boundaries.Semantic proximity Read ↗

Association between variants of zinc finger genes and psychiatric disorders: systematic review and meta-analysis.Semantic proximity Read ↗

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.