Article
Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants.
JAMA psychiatry - 1 Apr 2016
Hauberg Mads Engel, Roussos Panos, Grove Jakob, Børglum Anders Dupont, Mattheisen Manuel
Abstract excerpt
IMPORTANCE: The recent implication of 108 genomic loci in schizophrenia marked a great advancement in our understanding of the disease. Against the background of its polygenic nature there is a necessity to identify how schizophrenia risk genes interplay. As regulators of gene expression, microRNAs (miRNAs) have repeatedly been implicated in schizophrenia etiology. It is therefore of interest to establish their...
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