Article

The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder

2021-10-20

Abstract excerpt

<h4>SUMMARY</h4> Schizophrenia (SZ) and bipolar disorder (BP) are highly heritable major psychiatric disorders that share a substantial portion of genetic risk as well as their clinical manifestations. This raises a fundamental question of whether, and how, common neurobiological pathways translate their shared polygenic risks into shared clinical manifestations. The present study shows the miR-124-AMPAR pathway...

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Literature Corpus work: 9c76da67-b6fa-5142-a054-9dc0534931cb
DOI: 10.1101/2021.10.19.465053

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