Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders.

doi:10.1016/j.schres.2023.01.002

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Article

Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders.

Schizophrenia research - 1 Feb 2023

David Friederike S, Stein Frederike, Andlauer Till F M, Streit Fabian, Witt Stephanie H, Herms Stefan, Hoffmann Per, Heilmann-Heimbach Stefanie, Opel Nils, Repple Jonathan, Jansen Andreas, Nenadić Igor, Papiol Sergi, Heilbronner Urs, Kalman Janos L, Schaupp Sabrina K, Senner Fanny, Schulte Eva C, Falkai Peter G, Schulze Thomas G, Dannlowski Udo, Kircher Tilo, Rietschel Marcella, Nöthen Markus M, Krug Axel, Forstner Andreas J

Abstract excerpt

Major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia spectrum disorders (SZ) exhibit considerable phenotypic and genetic overlap. However, the contribution of genetic factors to their shared psychopathological symptom dimensions remains unclear. The present exploratory study investigated genetic contributions to the symptom dimensions "Depression", "Negative syndrome", "Positive formal...

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PMID: 36652833
DOI: 10.1016/j.schres.2023.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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