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Article

PRMT1 driven PTX3 regulates ferritinophagy in glioma.

Autophagy - 1 Jul 2023

Lathoria Kirti, Gowda Pruthvi, Umdor Sonia B, Patrick Shruti, Suri Vaishali, Sen Ellora

Abstract excerpt

Mutations in the Krebs cycle enzyme IDH1 (isocitrate dehydrogenase (NADP(+)) 1) are associated with better prognosis in gliomas. Though IDH1 mutant (IDH1R132H) tumors are characterized by their antiproliferative signatures maintained through hypermethylation of DNA and chromatin, mechanisms affecting cell death pathways in these tumors are not well elucidated. On investigating the crosstalk between the IDH1...

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Identifiers

PMID: 36647288
DOI: 10.1080/15548627.2023.2165757
PMCID: PMC10283415

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