Article
Transcriptional control of dendritic cell development and functions.
International review of cell and molecular biology - 1 Jan 2019
Amon Lukas, Lehmann Christian H K, Baranska Anna, Schoen Janina, Heger Lukas, Dudziak Diana
Abstract excerpt
Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable to induce efficient immune responses, but are also crucial to maintain peripheral tolerance and thereby inhibit autoimmune reactions. DCs bridge the innate and the adaptive immune system by presenting peptides of self and foreign antigens as peptide MHC complexes to T cells. These properties render DCs as interesting...
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