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Article

MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size.

eLife - 11 Jan 2023

Lafferty Michael J, Aygün Nil, Patel Niyanta K, Krupa Oleh, Liang Dan, Wolter Justin M, Geschwind Daniel H, de la Torre-Ubieta Luis, Stein Jason L

Abstract excerpt

Expression quantitative trait loci (eQTL) data have proven important for linking non-coding loci to protein-coding genes. But eQTL studies rarely measure microRNAs (miRNAs), small non-coding RNAs known to play a role in human brain development and neurogenesis. Here, we performed small-RNA sequencing across 212 mid-gestation human neocortical tissue samples, measured 907 expressed miRNAs, discovering 111 of which...

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Identifiers

PMID: 36629315
DOI: 10.7554/eLife.79488
PMCID: PMC9859047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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