Article
Mutation of the attractin gene impairs working memory in rats.
Brain and behavior - 1 Feb 2023
Liu Meng-Qi, Xue Cheng, Li Xiao-Hui, Ding Hong-Qun, Zhang Meng-Yu, Chen Kai, Li Ying, Gao Shu-Zhan, Xu Xi-Jia, Zhang Wei-Ning
Abstract excerpt
OBJECTIVE: Attractin (ATRN) is a widely expressed member of the cell adhesion and guidance protein family in humans that is closely related to cellular immunity and neurodevelopment. However, while previous studies in our laboratory have confirmed the effect of ATRN mutations on long-term memory, its specific role and the molecular mechanism by which it influences spatial cognition are poorly understood. METHODS:...
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