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Article

A role for α-adducin (ADD-1) in nematode and human memory.

The EMBO journal - 21 Mar 2012

Vukojevic Vanja, Gschwind Leo, Vogler Christian, Demougin Philippe, de Quervain Dominique J-F, Papassotiropoulos Andreas, Stetak Attila

Abstract excerpt

Identifying molecular mechanisms that underlie learning and memory is one of the major challenges in neuroscience. Taken the advantages of the nematode Caenorhabditis elegans, we investigated α-adducin (add-1) in aversive olfactory associative learning and memory. Loss of add-1 function selectively impaired short- and long-term memory without causing acquisition, sensory, or motor deficits. We showed that...

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Identifiers

PMID: 22307086
DOI: 10.1038/emboj.2012.14
PMCID: PMC3321180

Genes

ADD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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