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Article

Attractin Gene Deficiency in Rats Leads to Impairments in Both Activity and Spatial Learning and Memory.

Neuroscience - 1 Jul 2021

Li Xiao-Hui, Xue Cheng, Liu Meng-Qi, Zhang Meng-Yu, Zhou Yang, Xiao Xu, Wang Jia, Xu Xi-Jia, Shi Yun, Zhang Wei-Ning

Abstract excerpt

Attractin (ATRN), an autosomal recessive gene that is widely distributed in the brain, is involved in the execution of a variety of brain functions and associated with certain neuropsychiatric disorders. Here, we introduce a novel rat strain harboring a mutation in ATRN that was generated by knocking in ATRN-G505C via the CRISPR/Cas9 system. We assessed the behavioral performance of these mutant ATRN knock-in...

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PMID: 34000322
DOI: 10.1016/j.neuroscience.2021.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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