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Diagnostic value of H3F3A mutation and clinicopathological features of giant cell tumours in non-long bones

21 Dec 2022

Abstract excerpt

A histone H3F3A (H3.3) mutation involving a substitution in H3.3 G34 recently has been reported in GCTB within the frequency range (from 69 % to 96 %) and is a helpful diagnostic indicator of GCTB. However, the relationship between H3F3A mutations and the clinicopathological feature of GCTB involving non-long bones (irregular bones and small bones) is unclear. H3F3A mutations were observed in a cohort of...

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PMID: 36619849
DOI: 10.1016/j.jbo.2022.100467

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