Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt/BMP Mediated Metabolic Reprogramming Preserves Multipotency of Neural Crest-Like Stem Cells

7 Jan 2023

Abstract excerpt

Neural crest-like stem cells resembling embryonic neural crest cells (NCs) can be derived from adult human tissues such as the epidermis. However, these cells lose their multipotency rapidly in culture limiting their expansion for clinical use. Here, we show that the multipotency of keratinocyte-derived NCs (KC-NCs) can be preserved by activating the Wnt and BMP signaling axis, promoting expression of key...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurogenesis and neuroplasticity mechanisms
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36617947
DOI: 10.1093/stmcls/sxad001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt/BMP Mediated Metabolic Reprogramming Preserves Multipotency of Neural Crest-Like Stem CellsPMID 36617947Read ↗

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identifiedSemantic proximity Read ↗

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identifiedSemantic proximity Read ↗

Mitophagy promotes metabolic reprogramming to enhance keratinocyte migration via ANGPTL4 during wound healingSemantic proximity Read ↗

Glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signalingSemantic proximity Read ↗

Neural crest metabolism: At the crossroads of development and diseaseSemantic proximity Read ↗

Stage-resolved iPSC-to-motoneuron differentiation: Metabolic switch & mitochondrial remodelingSemantic proximity Read ↗

The metabolic kinase LKB1 shapes the enteric nervous system by mitigating the oxidative stress and p53 activitySemantic proximity Read ↗

Metabolic reprogramming as a novel regulator of skeletal muscle development and regenerationSemantic proximity Read ↗

Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and MelanocytesSemantic proximity Read ↗

Comparative Enzymatic Profiling of Enteric vs. Cortical Neural Stem Cells: Establishing a Methodological Foundation for Modeling Enteric NeurodegenerationSemantic proximity Read ↗

Restoration of <i>PKM1</i> improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolismSemantic proximity Read ↗

Notch and Wnt Signaling Modulation to Enhance DPSC Stemness and Therapeutic PotentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.