Article
Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements.
Genome research - 1 Jan 2023
Maroilley Tatiana, Flibotte Stephane, Jean Francesca, Rodrigues Alves Barbosa Victoria, Galbraith Andrew, Chida Afiya Razia, Cotra Filip, Li Xiao, Oncea Larisa, Edgley Mark, Moerman Don, Tarailo-Graovac Maja
Abstract excerpt
Genetic balancers in Caenorhabditis elegans are complex variants that allow lethal or sterile mutations to be stably maintained in a heterozygous state by suppressing crossover events. Balancers constitute an invaluable tool in the C. elegans scientific community and have been widely used for decades. The first/traditional balancers were created by applying X-rays, UV, or gamma radiation on C. elegans strains,...
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