Article
Identification and Characterization of Breakpoints and Mutations on Drosophila melanogaster Balancer Chromosomes.
G3 (Bethesda, Md.) - 5 Nov 2020
Miller Danny E, Kahsai Lily, Buddika Kasun, Dixon Michael J, Kim Bernard Y, Calvi Brian R, Sokol Nicholas S, Hawley R Scott, Cook Kevin R
Abstract excerpt
Balancers are rearranged chromosomes used in Drosophila melanogaster to maintain deleterious mutations in stable populations, preserve sets of linked genetic elements and construct complex experimental stocks. Here, we assess the phenotypes associated with breakpoint-induced mutations on commonly used third chromosome balancers and show remarkably few deleterious effects. We demonstrate that a breakpoint in p53...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.