Article
Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity.
Nature genetics - 29 Jan 2012
Andersen Erik C, Gerke Justin P, Shapiro Joshua A, Crissman Jonathan R, Ghosh Rajarshi, Bloom Joshua S, Félix Marie-Anne, Kruglyak Leonid
Abstract excerpt
The nematode Caenorhabditis elegans is central to research in molecular, cell and developmental biology, but nearly all of this research has been conducted on a single strain of C. elegans. Little is known about the population genomic and evolutionary history of this species. We characterized C. elegans genetic variation using high-throughput selective sequencing of a worldwide collection of 200 wild strains and...
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