Sequence analyses of relapsed or refractory diffuse large B-cell lymphomas unravel three genetic subgroups of patients and the GNA13 mutant as poor prognostic biomarker, results of LNH-EP1 study.

doi:10.1002/ajh.26835

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Sequence analyses of relapsed or refractory diffuse large B-cell lymphomas unravel three genetic subgroups of patients and the GNA13 mutant as poor prognostic biomarker, results of LNH-EP1 study.

American journal of hematology - 1 Apr 2023

Michot Jean-Marie, Quivoron Cyril, Sarkozy Clémentine, Danu Alina, Lazarovici Julien, Saleh Khalil, El-Dakdouki Yolla, Goldschmidt Vincent, Bigenwald Camille, Dragani Matteo, Bahleda Rastislav, Baldini Capucine, Arfi-Rouche Julia, Martin-Romano Patricia, Tselikas Lambros, Gazzah Anas, Hollebecque Antoine, Lacroix Ludovic, Ghez David, Vergé Veronique, Marzac Christophe, Cotteret Sophie, Rahali Wassila, Soria Jean-Charles, Massard Christophe, Bernard Olivier A, Dartigues Peggy, Camara-Clayette Valérie, Ribrag Vincent

Abstract excerpt

Advances in molecular profiling of newly diagnosed diffuse large B-cell lymphoma (DLBCL) have recently refine genetic subgroups. Genetic subgroups remain undetermined at the time of relapse or refractory (RR) disease. This study aims to decipher genetic subgroups and search for prognostic molecular biomarkers in patients with RR-DLBCL. From 2015 to 2021, targeted next-generation sequencing analyses of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Biomarkers

Share to High-Throughput Nucleotide Sequencing

Share to Lymphoma, Large B-Cell, Diffuse

Share to Neoplasm Recurrence, Local

Share to Prognosis

Share to Proto-Oncogene Proteins c-bcl-2

Source

Open in PubMed

Identifiers

PMID: 36606708
DOI: 10.1002/ajh.26835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence analyses of relapsed or refractory diffuse large B-cell lymphomas unravel three genetic subgroups of patients and the GNA13 mutant as poor prognostic biomarker, results of LNH-EP1 study.PMID 36606708Read ↗

Simplified algorithm for genetic subtyping in diffuse large B-cell lymphomaSemantic proximity Read ↗

Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma.Semantic proximity Read ↗

Genetic Map of Relapsed and Refractory Diffuse Large B-cell Lymphoma: A Systemic Review and Association AnalysisSemantic proximity Read ↗

Molecular classification and therapeutics in diffuse large B-cell lymphomaSemantic proximity Read ↗

Prognostic Analysis of Diffuse Large B-Cell Lymphoma Patients Based on Clinical Characteristics, TP53 Mutation Status, and Number of Co-mutated GenesSemantic proximity Read ↗

Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network reportSemantic proximity Read ↗

High-risk subgroup and associated genes identified by next generation sequencing in diffuse large B cell lymphoma.Semantic proximity Read ↗

High-grade B-cell lymphoma not otherwise specified, with diffuse large B-cell lymphoma gene expression signatures: Genomic analysis and potential therapeutics.Semantic proximity Read ↗

Genetic and transcriptomic analyses of diffuse large B-cell lymphoma patients with poor outcomes within two years of diagnosisSemantic proximity Read ↗

Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas.Semantic proximity Read ↗

Genetic heterogeneity of diffuse large B-cell lymphoma.Semantic proximity Read ↗

Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.