Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of deleterious nsSNPs in human HGF gene: in silico approach.

Journal of biomolecular structure & dynamics - 1 Jan 2023

Hoda Anila, Lika Çekani Mirela, Kolaneci Valbona

Abstract excerpt

HGF is a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in different cells and tissues. Several bioinformatics tools and in silico methods were used to identify most deleterious nsSNPs that might change the structure and function of HGF protein. The in silico tools such as SIFT, SNP&GO and PolyPhen2 were used to distinguish deleterious nsSNPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Hepatocyte Growth Factor
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Stability

Source

Identifiers

PMID: 36598356
DOI: 10.1080/07391102.2022.2164060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of deleterious nsSNPs in human HGF gene: in silico approach.PMID 36598356Read ↗

An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET GeneSemantic proximity Read ↗

SNPs of bovine HGF gene and their association with growth traits in Nanyang cattle.Semantic proximity Read ↗

In silico analysis predicting effects of deleterious SNPs of human RASSF5 gene on its structure and functions.Semantic proximity Read ↗

Genetic Study of HGF-MET Signaling Pathway in Primary Lymphedema Patients: Supporting Evidence for Loss of Function Variants in HGF.Semantic proximity Read ↗

<i>In Silico</i> Analysis Predicting Effects of Deleterious SNPs of Human <i>RASSF5</i> Gene on its Structure and FunctionsSemantic proximity Read ↗

Association between hepatocyte growth factor gene polymorphism and essential hypertension.Semantic proximity Read ↗

In-silico assessment of high-risk non-synonymous SNPs in ADAMTS3 gene associated with Hennekam syndrome and their impact on protein stability and function.Semantic proximity Read ↗

Computational analysis for the determination of deleterious nsSNPs in human MTHFR gene.Semantic proximity Read ↗

Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA).Semantic proximity Read ↗

Identification of 21 single nucleotide polymorphisms in human hepatocyte growth factor gene and association with blood pressure and carotid atherosclerosis in the Japanese population.Semantic proximity Read ↗

Computational and structural analysis of deleterious functional SNPs in ARNT oncogene.Semantic proximity Read ↗

Prediction of potential deleterious nonsynonymous single nucleotide polymorphisms of HIF1A gene: A computational approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.