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Article

Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA).

Annals of human genetics - 1 Jul 2015

Larson Nicholas B, Berardi Cecilia, Decker Paul A, Wassel Christina L, Kirsch Phillip S, Pankow James S, Sale Michele M, de Andrade Mariza, Sicotte Hugues, Tang Weihong, Hanson Naomi Q, Tsai Michael Y, Taylor Kent D, Bielinski Suzette J

Abstract excerpt

Hepatocyte growth factor (HGF) is a mesenchyme-derived pleiotropic factor that regulates cell growth, motility, mitogenesis, and morphogenesis in a variety of cells, and increased serum levels of HGF have been linked to a number of clinical and subclinical cardiovascular disease phenotypes. However, little is currently known regarding which genetic factors influence HGF levels, despite evidence of substantial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25998175
DOI: 10.1111/ahg.12119
PMCID: PMC4474777

Genes

HGF
HGFAC
FASN

Variants

rs16844364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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