Article
Identification of 21 single nucleotide polymorphisms in human hepatocyte growth factor gene and association with blood pressure and carotid atherosclerosis in the Japanese population.
Atherosclerosis - 1 Apr 2004
Takiuchi Shin, Mannami Toshifumi, Miyata Toshiyuki, Kamide Kei, Tanaka Chihiro, Kokubo Yoshihiro, Koyama Yuko, Inamoto Nozomu, Katsuya Tomohiro, Iwai Naoharu, Kawano Yuhei, Ogihara Toshio, Tomoike Hitonobu
Abstract excerpt
It has been suggested that circulating concentrations of hepatocyte growth factor (HGF) are increased in individuals with vascular endothelial damage, such as in hypertensive patients and subjects with atherosclerosis. Because the influence of genetic variation of HGF has not been examined, we identified single nucleotide polymorphisms (SNPs) in the HGF gene, and investigated the association between these SNPs...
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