Article
Association between hepatocyte growth factor gene polymorphism and essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Apr 2004
Motone Masaharu, Katsuya Tomohiro, Ishikawa Kazuhiko, Iwashima Yoshio, Sugimoto Ken, Yamamoto Koichi, Fu Yuxiao, Matsuo Akiko, Ohishi Mitsuru, Rakugi Hiromi, Ogihara Toshio
Abstract excerpt
Hepatocyte growth factor (HGF) is a growth factor which contributes to protection and/or repair of vascular endothelial cells. Serum HGF level is elevated in response to hypertensive organ damage, which suggests that blood pressure regulation may be affected by HGF gene polymorphisms via serum HGF. To examine the interaction between a HGF gene polymorphism and hypertension, we carried out a case-control study....
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